Autoren-Infos | Literaturhinweise | Sonstiges
Ausgabe 7/8-2022
Inhalt:
Damit in der Zahnhaltung erst gar nicht die Pulpa ins Spiel kommt, ist modernes Kariesmanagement gefragt. Hier erhalten auch versierte Zahnärzte und Zahnärztinnen von Prof. Dr. Nadine Schlüter und ihrem Autorenteam auf Basis des aktuellen Verständnis der Kariesentstehung neue Empfehlungen zur Vorbeugung, Diagnostik und Behandlung der Karies für den Praxisalltag.
Über die Autorin:
Dr. Maxi Katharina Müller
Zahnärztin und wissenschaftliche Mitarbeiterin, Autorin
Universitätsklinikum Freiburg
Department f. Zahn-, Mund- u. Kieferheilkunde
Klinik für Zahnerhaltungskunde und Parodontologie
Hugstetter Str. 55
D-79106 Freiburg i. Br.
Tel.: +49 761-270 49560
E-Mail: maxi.mueller@uniklinik-freiburg.de
www.uniklinik-freiburg.de/de
Werdegang und Vita
Seit 2018: Assistenzzahnärztin Klinik für Zahnerhaltung und Parodontologie, wissenschaftliche Mitarbeiterin der Stiftungsprofessur für Kariesforschung, Department Zahn-, Mund- und Kieferheilkunde, Universitätsklinikum Freiburg
2021: Promotion zum Dr. med. dent., Albert-Ludwigs-Universität Freiburg
2016: Staatsexamen Zahnmedizin, Albert-Ludwigs-Universität Freiburg
2011 – 2016: Studium der Zahnmedizin, Albert-Ludwigs-Universität Freiburg
Mitgliedschaften: Deutsche Gesellschaft für Zahn-, Mund- und Kieferheilkunde (DGZMK), Deutsche Gesellschaft für Zahnerhaltung (DGZ) inklusive Untergesellschaft, Deutsche Gesellschaft für Endodontologie und Zahnärztliche Traumatologie (DGET)
Prof. Dr. med. dent. Nadine Schlüter
Klinikdirektorin, Fachzahnärztin und Autorin
Klinik für Zahnerhaltung, Parodontologie und Präventivzahnmedizin,
Medizinische Hochschule Hannover
Carl-Neuberg-Str. 1
D-30625 Hannover
www.mhh.de
Werdegang und Vita
Seit 2022: Direktorin der Klinik für Zahnerhaltung, Parodontologie und Präventivzahnmedizin der Medizinischen Hochschule Hannover
2022: Annahme der W3-Professur Zahnerhaltung und Parodontologie an der Medizinischen Hochschule Hannover
Seit 2020: Autorin der S3-Leitlinie Kariesprävention (Autorenteam: Geurtsen, Hellwig, Schlüter, Koordination: Rupf)
2020: Spezialistin im Bereich Zahnerhaltung (präventiv und restaurativ) Deutsche Gesellschaft für Zahnerhaltung
2019 – 2022: Studiendekanin für das Fach Zahnmedizin an der Albert-Ludwigs-Universität in Freiburg im Breisgau
2018 – 2021: Mitglied des wissenschaftlichen Beirats der Zeitschrift Das Deutsche Zahnärzteblatt
Seit 2018: Mitglied des wissenschaftlichen Beirats der Informationsstelle für Kariesprophylaxe (Frankfurt)
Seit 2018: Mitglied des wissenschaftlichen Beirats der Zeitschrift Oralprophylaxe & Kinderzahnheilkunde
Seit 2017: Associate Editor des European Journal of Oral Sciences für den gesamten Bereich Zahnhartgewebe
Seit 2017: Mitglied der Leitliniengruppe Chronische KHK als Repräsentantin der DGZMK
2015 – 2022: Leiterin des Bereichs Kariesforschung, Klinik für Zahnerhaltungskunde und Parodontologie, Universitätsklinikum Freiburg
2015: Ruf auf die W3-Stiftungsprofessur für Kariesforschung an der Albert-Ludwigs-Universität in Freiburg
2014 – 2018: Treasurer und Executive Board Member der European Organisation for Caries Research (ORCA)
2013: Venia Legendi, Justus-Liebig-Universität Gießen
2012 – 2013: Advisory Board Member der European Organisation for Caries
Research (ORCA)
2012: Habilitation im Fach Zahnmedizin, Justus-Liebig-Universität Gießen
2012: Forschungsaufenthalt an der Klinik für Zahnerhaltung, Präventiv- und
Kinderzahnmedizin der Universität Bern (Leitung: Prof. Dr. Lussi); Arbeitsgruppe Dental Materials
2011 – 2017: Gründungsmitglied und Generalsekretärin der Deutschen Gesellschaft für Präventivzahnmedizin (dgpzm)
2011 – 2015: Oberärztin in der Poliklinik für Zahnerhaltungskunde und Präventive Zahnheilkunde des Medizinischen Zentrums für Zahn-, Mund- und Kieferheilkunde der Justus-Liebig-Universität in Gießen
2004: Promotion zum Dr. med. dent., Georg-August-Universität Göttingen
2002 – 2011:Wissenschaftliche Mitarbeiterin in der Poliklinik für Zahnerhaltungskunde und Präventive Zahnheilkunde des Medizinischen Zentrums für Zahn-, Mund- und Kieferheilkunde der Justus-Liebig-Universität in Gießen
2001: Staatsexamen Zahnmedizin, Georg-August-Universität Göttingen
1996 – 2001: Studium der Zahnmedizin, Georg-August-Universität Göttingen
Mitgliedschaften (Auswahl): Deutsche Gesellschaft für Zahn-, Mund- und Kieferheilkunde (DGZMK), Deutsche Gesellschaft für Zahnerhaltung (DGZ) inklusive UntergesellschaftenEuropean Organisation for Caries Research (ORCA), Deutsche Gesellschaft für Alterszahnmedizin, Arbeitskreis für die Weiterentwicklung der Lehre in der Zahnmedizin, Deutsche Krebsgesellschaft (DKG) inklusive Untergesellschaften
Auszeichnungen (Auswahl): Wrigley Prophylaxepreis (2021, 2012, 2008, 2006), IADR Basil G. Bibby Young Investigator Award (2017), Prevention Award der European Federation for Conservative Dentistry (EFCD) (2017), DGZ Posterpreis (2011), Young Investigators Award der European Organisation for Caries Research – ORCA (2010), 2005 Förderpreis Klinische Forschung des KKS Marburg (2005), Alex-Motsch-Studentenpreis (2001)
Dr. Benedikt Luka (Korresp. Autor)
Oberarzt und Autor
Klinik für Zahnerhaltung, Parodontologie und Präventivzahnmedizin,
Medizinische Hochschule Hannover
Carl-Neuberg-Str. 1
D-30625 Hannover
www.mhh.de
Literatur
1. Tanner ACR, Kressirer CA, Rothmiller S, Johansson I, Chalmers NI. The Caries Microbiome: Implications for Reversing Dysbiosis. Adv Dent Res. 2018;29: 78–85. doi:10.1177/0022034517736496
2. Chhour K-L, Nadkarni MA, Byun R, Martin FE, Jacques NA, Hunter N. Molecular analysis of microbial diversity in advanced caries. J Clin Microbiol. 2005;43: 843–849. doi:10.1128/JCM.43.2.843-849.2005
3. Loesche WJ, Eklund S, Earnest R, Burt B. Longitudinal investigation of bacteriology of human fissure decay: epidemiological studies in molars shortly after eruption. Infect Immun. 1984;46: 765–772.
4. Takahashi N, Nyvad B. The role of bacteria in the caries process: ecological perspectives. J Dent Res. 2011;90: 294–303. doi:10.1177/0022034510379602
5. Gross EL, Leys EJ, Gasparovich SR, Firestone ND, Schwartzbaum JA, Janies DA, et al. Bacterial 16S sequence analysis of severe caries in young permanent teeth. J Clin Microbiol. 2010;48: 4121–4128. doi:10.1128/JCM.01232-10
6. Nascimento MM, Zaura E, Mira A, Takahashi N, Ten Cate JM. Second Era of OMICS in Caries Research: Moving Past the Phase of Disillusionment. J Dent Res. 2017;96: 733–740. doi:10.1177/0022034517701902
7. Marsh PD. Microbial ecology of dental plaque and its significance in health and disease. Adv Dent Res. 1994;8: 263–271. doi:10.1177/08959374940080022001
8. Burne RA. Getting to Know “The Known Unknowns”: Heterogeneity in the Oral Microbiome. Adv Dent Res. 2018;29: 66–70. doi:10.1177/0022034517735293
9. Dawes C. What is the critical pH and why does a tooth dissolve in acid? J Can Dent Assoc. 2003;69: 722–724.
10. Horiuchi M, Washio J, Mayanagi H, Takahashi N. Transient acid-impairment of growth ability of oral Streptococcus, Actinomyces, and Lactobacillus: a possible ecological determinant in dental plaque. Oral Microbiol Immunol. 2009;24: 319–324. doi:10.1111/j.1399-302X.2009.00517.x
11. Takahashi N, Yamada T. Acid-induced acid tolerance and acidogenicity of non-mutans streptococci. Oral Microbiol Immunol. 1999;14: 43–48. doi:10.1034/j.1399-302x.1999.140105.x
12. Pitts NB, Twetman S, Fisher J, Marsh PD. Understanding dental caries as a non-communicable disease. Br Dent J. 2021;231: 749–753. doi:10.1038/s41415-021-3775-4
13. Marsh PD. In Sickness and in Health-What Does the Oral Microbiome Mean to Us? An Ecological Perspective. Adv Dent Res. 2018;29: 60–65. doi:10.1177/0022034517735295
14. Takahashi N, Nyvad B. Ecological Hypothesis of Dentin and Root Caries. Caries Res. 2016;50: 422–431. doi:10.1159/000447309
15. Moreno EC, Aoba T. Comparative solubility study of human dental enamel, dentin, and hydroxyapatite. Calcif Tissue Int. 1991;49: 6–13. doi:10.1007/BF02555895
16. Shellis RP. A scanning electron-microscopic study of solubility variations in human enamel and dentine. Arch Oral Biol. 1996;41: 473–484.
17. Tjäderhane L, Larjava H, Sorsa T, Uitto VJ, Larmas M, Salo T. The activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesions. J Dent Res. 1998;77: 1622–1629. doi:10.1177/00220345980770081001
18. Nascimento FD, Minciotti CL, Geraldeli S, Carrilho MR, Pashley DH, Tay FR, et al. Cysteine cathepsins in human carious dentin. J Dent Res. 2011;90: 506–511. doi:10.1177/0022034510391906
19. Kassebaum NJ, Smith AGC, Bernabé E, Fleming TD, Reynolds AE, Vos T, et al. Global, Regional, and National Prevalence, Incidence, and Disability-Adjusted Life Years for Oral Conditions for 195 Countries, 1990–2015: A Systematic Analysis for the Global Burden of Diseases, Injuries, and Risk Factors. J Dent Res. 2017;96: 380–387. doi:10.1177/0022034517693566
20. Cholmakow-Bodechtel C. Fünfte Deutsche Mundgesundheitsstudie (DMS V). Jordan AR, Micheelis W, editors. Köln: Deutscher Zahnärzte Verlag DÄV; 2016.
21. Cholmakow-Bodechtel C. Fünfte Deutsche Mundgesundheitsstudie (DMS V). Jordan AR, Micheelis W, editors. Köln: Deutscher Zahnärzte Verlag DÄV; 2016.
22. World Health Organization. Guideline: sugars intake for adults and children. Geneva: World Health Organization; 2015. Abrufbar unter apps.who.int/iris/handle/10665/149782
23. Geurtsen W, Hellwig E, Klimek J. Kariesprophylaxe bei bleibenden Zähnen – grundlegende Empfehlungen. S2k-Leitlinie der DGZ, DGZMK, DGKiZ, DGPro. 2016. Abrufbar unter www.dgzmk.de
24. Radwan-Oczko M, Duś-Ilnicka I, Richards P, Thomsen AM, Rasmussen C. Evaluation of Oral Health Status and Oral Care of Patients with Rheumatoid Arthritis. Mallineni SK, editor. Int J Dent. 2020;2020: 1–7. doi:10.1155/2020/8896766
25. Mese H, Matsuo R. Salivary secretion, taste and hyposalivation. J Oral Rehabil. 2007;34: 711–723. doi:10.1111/j.1365-2842.2007.01794.x
26. Mossman K, Shatzman A, Chencharick J. Long-term effects of radiotherapy on taste and salivary function in man. Int J Radiat Oncol. 1982;8: 991–997. doi:10.1016/0360-3016(82)90166-3
27. Sakai M, Kazui H, Shigenobu K, Komori K, Ikeda M, Nishikawa T. Gustatory Dysfunction as an Early Symptom of Semantic Dementia. Dement Geriatr Cogn Disord Extra. 2017;7: 395–405. doi:10.1159/000481854
28. Mysels, MD, MBA DJ, Sullivan, MD, PhD MA. The relationship between opioid and sugar intake: Review of evidence and clinical applications. J Opioid Manag. 2010;6: 445–452. doi:10.5055/jom.2010.0043
29. Riley P, Moore D, Ahmed F, Sharif MO, Worthington HV. Xylitol-containing products for preventing dental caries in children and adults. Cochrane Oral Health Group, editor. Cochrane Database Syst Rev. 2015 [cited 13 Apr 2022]. doi:10.1002/14651858.CD010743.pub2
30. Scheinin A, Mäkinen KK, Ylitalo K. Turku sugar studies V: Final report on the effect of sucrose, fructose and xylitol diets on the caries incidence in man. Acta Odontol Scand. 1976;34: 179–216. doi:10.3109/00016357608997711
31. Rethman MP, Beltrán-Aguilar ED, Billings RJ, Burne RA, Clark M, Donly KJ, et al. Nonfluoride caries-preventive agents. J Am Dent Assoc. 2011;142: 1065–1071. doi:10.14219/jada.archive.2011.0329
32. Powered versus manual toothbrushing for oral health – Yaacob, M – 2014 | Cochrane Library. [cited 28 Jan 2022]. Abrufbar unter www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD002281.pub3/full
33. Pitchika V, Jordan R, Micheelis W, Welk A, Kocher T, Holtfreter B. Impact of Powered Toothbrush Use and Interdental Cleaning on Oral Health. J Dent Res. 2021;100: 487–495. doi:10.1177/0022034520973952
34. Schlueter N, Fiedler S, Mueller M, Walter C, Difloe-Geisert JC, Vach K, et al. Efficacy of a sonic toothbrush on plaque removal—A video-controlled explorative clinical trial. PLOS ONE. 2021;16: e0261496. doi:10.1371/journal.pone.0261496
35. Deacon SA, Glenny A-M, Deery C, Robinson PG, Heanue M, Walmsley AD, et al. Different powered toothbrushes for plaque control and gingival health. Cochrane Oral Health Group, editor. Cochrane Database Syst Rev. 2010;2020. doi:10.1002/14651858.CD004971.pub2
36. Winterfeld T, Schlueter N, Harnacke D, Illig J, Margraf-Stiksrud J, Deinzer R, et al. Toothbrushing and flossing behaviour in young adults–a video observation. Clin Oral Investig. 2015;19: 851–858. doi:10.1007/s00784-014-1306-2
37. Muller-Bolla M, Courson F. Toothbrushing methods to use in children: a systematic review. Oral Health Prev Dent. 2013;11: 341–347. doi:10.3290/j.ohpd.a30602
38. Wainwright J, Sheiham A. An analysis of methods of toothbrushing recommended by dental associations, toothpaste and toothbrush companies and in dental texts. Br Dent J. 2014;217: E5. doi:10.1038/sj.bdj.2014.651
39. Schlueter N, Klimek J, Ganss C. Relationship between plaque score and video-monitored brushing performance after repeated instruction—a controlled, randomised clinical trial. Clin Oral Investig. 2013;17: 659–667. doi:10.1007/s00784-012-0744-y
40. Ng E, Lim LP. An Overview of Different Interdental Cleaning Aids and Their Effectiveness. Dent J. 2019;7: 56. doi:10.3390/dj7020056
41. Amarasena N, Gnanamanickam ES, Miller J. Effects of interdental cleaning devices in preventing dental caries and periodontal diseases: a scoping review. Aust Dent J. 2019;64: 327–337. doi:10.1111/adj.12722
42. Worthington HV, MacDonald L, Poklepovic Pericic T, Sambunjak D, Johnson TM, Imai P, et al. Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal diseases and dental caries. Cochrane Database Syst Rev. 2019;4: CD012018. doi:10.1002/14651858.CD012018.pub2
43. Jaeggi T, Lussi A. Interdental brushes. Swiss Dent J. 2019;129: 944–945.
44. A systematic review of oral health in people with multiple sclerosis – Manchery – 2020 – Community Dentistry and Oral Epidemiology – Wiley Online Library. [cited 13 Apr 2022]. Available: onlinelibrary.wiley.com/doi/full/10.1111/cdoe.12512
45. de Souza S, Bansal RK, Galloway J. Rheumatoid arthritis – an update for general dental practitioners. Br Dent J. 2016;221: 667–673. doi:10.1038/sj.bdj.2016.866
46. Ogaard B. Effects of fluoride on caries development and progression in vivo. J Dent Res. 1990;69 Spec No: 813–819; discussion 820-823. doi:10.1177/00220345900690S155
47. Rølla G. On the role of calcium fluoride in the cariostatic mechanism of fluoride. Acta Odontol Scand. 1988;46: 341–345. doi:10.3109/00016358809004786
48. Featherstone JD. Prevention and reversal of dental caries: role of low level fluoride. Community Dent Oral Epidemiol. 1999;27: 31–40. doi:10.1111/j.1600-0528.1999.tb01989.x
49. AWMF: Detail. [cited 26 Jan 2022]. Abrufbar unter www.awmf.org/leitlinien
50. Brush Teeth – American Dental Association. [cited 26 Jan 2022]. Abrufbar unter www.mouthhealthy.org/en/az-topics/b/brushing-your-teeth
51. Meyer-Lueckel H, Machiulskiene V, Giacaman RA. How to Intervene in the Root Caries Process? Systematic Review and Meta-Analyses. Caries Res. 2019;53: 599–608. doi:10.1159/000501588
52. Paris S, Banerjee A, Bottenberg P, Breschi L, Campus G, Doméjean S, et al. How to Intervene in the Caries Process in Older Adults: A Joint ORCA and EFCD Expert Delphi Consensus Statement. Caries Res. 2020;54: 459–465. doi:10.1159/000510843
53. Walsh T, Worthington HV, Glenny A-M, Marinho VC, Jeroncic A. Fluoride toothpastes of different concentrations for preventing dental caries. Cochrane Database Syst Rev. 2019;3: CD007868. doi:10.1002/14651858.CD007868.pub3
54. Neue Empfehlungen für Kinderzahnpasten mit Fluorid | dgpzm. [cited 28 Jan 2022]. Abrufbar unter www.dgpzm.de
55. Hellwig E, Schiffner U, Schulte A. Fluoridierungsmaßnahmen (S2k). 2013 [cited 26 Jan 2022]. Abrufbar unter www.dgzmk.de
56. O Mullane DM, Baez RJ, Jones S, Lennon MA, Petersen PE, Rugg-Gunn AJ, et al. Fluoride and oral health. Community Dent Health. 2016;33: 69–99.
57. Dawes C, Pedersen AML, Villa A, Ekström J, Proctor GB, Vissink A, et al. The functions of human saliva: A review sponsored by the World Workshop on Oral Medicine VI. Arch Oral Biol. 2015;60: 863–874. doi:10.1016/j.archoralbio.2015.03.004
58. Chan AKY, Tamrakar M, Jiang CM, Lo ECM, Leung KCM, Chu C-H. Common Medical and Dental Problems of Older Adults: A Narrative Review. Geriatrics. 2021;6: 76. doi:10.3390/geriatrics6030076
59. Ritter AV, Shugars DA, Bader JD. Root caries risk indicators: a systematic review of risk models: Root caries risk models systematic review. Community Dent Oral Epidemiol. 2010;38: 383–397. doi:10.1111/j.1600-0528.2010.00551.x
60. Marinho VCC. Cochrane reviews of randomized trials of fluoride therapies for preventing dental caries. Eur Arch Paediatr Dent. 2009;10: 183–191. doi:10.1007/BF03262681
61. Ekstrand KR. High Fluoride Dentifrices for Elderly and Vulnerable Adults: Does It Work and if So, Then Why? Caries Res. 2016;50: 15–21. doi:10.1159/000443021
62. Marinho VC, Worthington HV, Walsh T, Chong L-Y. Fluoride gels for preventing dental caries in children and adolescents. Cochrane Oral Health Group, editor. Cochrane Database Syst Rev. 2015;2021. doi:10.1002/14651858.CD002280.pub2
63. Marinho VC, Chong L-Y, Worthington HV, Walsh T. Fluoride mouthrinses for preventing dental caries in children and adolescents. Cochrane Oral Health Group, editor. Cochrane Database Syst Rev. 2016;2021. doi:10.1002/14651858.CD002284.pub2
64. Zhang J, Sardana D, Li KY, Leung KCM, Lo ECM. Topical Fluoride to Prevent Root Caries: Systematic Review with Network Meta-analysis. J Dent Res. 2020;99: 506–513. doi:10.1177/0022034520906384
65. Sardana D, Zhang J, Ekambaram M, Yang Y, McGrath CP, Yiu CKY. Effectiveness of professional fluorides against enamel white spot lesions during fixed orthodontic treatment: A systematic review and meta-analysis. J Dent. 2019;82: 1–10. doi:10.1016/j.jdent.2018.12.006
66. Marinho VC, Worthington HV, Walsh T, Clarkson JE. Fluoride varnishes for preventing dental caries in children and adolescents. Cochrane Oral Health Group, editor. Cochrane Database Syst Rev. 2013 [cited 24 Jun 2022]. doi:10.1002/14651858.CD002279.pub2
67. Hu H, Feng C, Jiang Z, Wang L, Shrestha S, Yan J, et al. Effectiveness of remineralizing agents in the prevention and reversal of orthodontically induced white spot lesions: a systematic review and network meta-analysis. Clin Oral Investig. 2020;24: 4153–4167. doi:10.1007/s00784-020-03610-z
68. Tasios T, Papageorgiou SN, Papadopoulos MA, Tsapas A, Haidich A. Prevention of orthodontic enamel demineralization: A systematic review with meta‐analyses. Orthod Craniofac Res. 2019;22: 225–235. doi:10.1111/ocr.12322
69. Benson PE, Parkin N, Dyer F, Millett DT, Germain P. Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment. Cochrane Oral Health Group, editor. Cochrane Database Syst Rev. 2019 [cited 14 Jun 2022]. doi:10.1002/14651858.CD003809.pub4
70. Gupta A, Sharda S, Nishant, Shafiq N, Kumar A, Goyal A. Topical fluoride-antibacterial agent combined therapy versus topical fluoride monotherapy in preventing dental caries: a systematic review and meta-analysis. Eur Arch Paediatr Dent. 2020;21: 629–646. doi:10.1007/s40368-020-00561-7
71. Li F, Jiang P, Yu F, Li C, Wu S, Zou J, et al. Comparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a Systematic Review and Meta-analysis. Sci Rep. 2020;10: 2578. doi:10.1038/s41598-020-59564-5
72. Kashbour W, Gupta P, Worthington HV, Boyers D. Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents. Cochrane Oral Health Group, editor. Cochrane Database Syst Rev. 2020 [cited 24 Jun 2022]. doi:10.1002/14651858.CD003067.pub5
73. Petersson LG. Fluoride Mouthrinses and Fluoride Varnishes. Caries Res. 1993;27: 35–42. doi:10.1159/000261600
74. Gluzman R, Katz RV, Frey BJ, McGowan R. Prevention of root caries: a literature review of primary and secondary preventive agents: PREVENTION OF ROOT CARIES IN OLDER ADULTS: A SUMMARY. Spec Care Dentist. 2013;33: 133–140. doi:10.1111/j.1754-4505.2012.00318.x
75. Van Strydonck DAC, Slot DE, Van der Velden U, Van der Weijden F. Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review. J Clin Periodontol. 2012;39: 1042–1055. doi:10.1111/j.1600-051X.2012.01883.x
76. Rethman MP, Beltran-Aguilar ED, Billings RJ, Burne RA, Clark M, Donly KJ, et al. Non-fluoride caries preventive agents: full report of a systematic review and evidence-based recommendations. Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet]. Centre for Reviews and Dissemination (UK); 2011. Abrufbar unter www.ncbi.nlm.nih.gov/books/NBK137902/
77. Slot DE, Vaandrager NC, Van Loveren C, Van Palenstein Helderman WH, Van der Weijden GA. The Effect of Chlorhexidine Varnish on Root Caries: A Systematic Review. Caries Res. 2011;45: 162–173. doi:10.1159/000327374
78. Lemire JA, Harrison JJ, Turner RJ. Antimicrobial activity of metals: mechanisms, molecular targets and applications. Nat Rev Microbiol. 2013;11: 371–384. doi:10.1038/nrmicro3028
79. Kruse AB, Schlueter N, Kortmann VK, Frese C, Anderson A, Wittmer A, et al. Long-Term Use of Oral Hygiene Products Containing Stannous and Fluoride Ions: Effect on Viable Salivary Bacteria. Antibiotics. 2021;10: 481. doi:10.3390/antibiotics10050481
80. Pini NIP, Schlueter N, Sundfeld D, Semper Hogg W, Santos-Silva AR, Lopes MA, et al. Efficacy of Stannous Ions on Enamel Demineralization under Normal and Hyposalivatory Conditions: A Controlled Randomized in situ Pilot Trial. Caries Res. 2017;51: 543–553. doi:10.1159/000479041
81. Beiraghi S, Rosen S, Beck F. The effect of stannous and sodium fluoride on coronal caries, root caries and bone loss in rice rats. Arch Oral Biol. 1990;35: 79–80. doi:10.1016/0003-9969(90)90120-Y
82. Philip N. State of the Art Enamel Remineralization Systems: The Next Frontier in Caries Management. Caries Res. 2019;53: 284–295. doi:10.1159/000493031
83. Li J, Huang Z, Mei L, Li G, Li H. Anti-Caries Effect of Arginine-Containing Formulations in vivo: A Systematic Review and Meta-Analysis. Caries Res. 2015;49: 606–617. doi:10.1159/000435894
84. Gugnani N, Pandit I, Srivastava N, Gupta M, Sharma M. International Caries Detection and Assessment System (ICDAS): A New Concept. Int J Clin Pediatr Dent. 2011;4: 93–100. doi:10.5005/jp-journals-10005-1089
85. Dikmen B. Icdas II criteria (international caries detection and assessment system). J Istanb Univ Fac Dent. 2015;49: 63–72. doi:10.17096/jiufd.38691
86. Rosa MI, Schambeck VS, Dondossola ER, Alexandre MC, Tuon L, Grande AJ, et al. Laser fluorescence of caries detection in permanent teeth in vitro: a systematic review and meta-analysis. J Evid-Based Med. 2016;9: 213–224. doi:10.1111/jebm.12227
87. Huth KC, Lussi A, Gygax M, Thum M, Crispin A, Paschos E, et al. In vivo performance of a laser fluorescence device for the approximal detection of caries in permanent molars. J Dent. 2010;38: 1019–1026. doi:10.1016/j.jdent.2010.09.001
88. Diniz MB, Rodrigues JA, Rodrigues J de A, de Paula AB, Cordeiro R de CL. In vivo evaluation of laser fluorescence performance using different cut-off limits for occlusal caries detection. Lasers Med Sci. 2009;24: 295–300. doi:10.1007/s10103-008-0547-1
89. Davies GM, Worthington HV, Clarkson JE, Thomas P, Davies RM. The use of fibre-optic transillumination in general dental practice. Br Dent J. 2001;191: 145–147. doi:10.1038/sj.bdj.4801123
90. Alamoudi NM, Khan JA, El-Ashiry EA, Felemban OM, Bagher SM, Al-Tuwirqi AA. Accuracy of the DIAGNOcam and bitewing radiographs in the diagnosis of cavitated proximal carious lesions in primary molars. Niger J Clin Pract. 2019;22: 1576–1582. doi:10.4103/njcp.njcp_237_19
91. Marmaneu-Menero A, Iranzo-Cortés JE, Almerich-Torres T, Ortolá-Síscar JC, Montiel-Company JM, Almerich-Silla JM. Diagnostic Validity of Digital Imaging Fiber-Optic Transillumination (DIFOTI) and Near-Infrared Light Transillumination (NILT) for Caries in Dentine. J Clin Med. 2020;9: 420. doi:10.3390/jcm9020420
92. Schwendicke F, Splieth C, Breschi L, Banerjee A, Fontana M, Paris S, et al. When to intervene in the caries process? An expert Delphi consensus statement. Clin Oral Investig. 2019;23: 3691–3703. doi:10.1007/s00784-019-03058-w
93. Bratthall D, Hänsel Petersson G. Cariogram–a multifactorial risk assessment model for a multifactorial disease. Community Dent Oral Epidemiol. 2005;33: 256–264. doi:10.1111/j.1600-0528.2005.00233.x
94. Splieth CH, Ekstrand KR, Alkilzy M, Clarkson J, Meyer-Lueckel H, Martignon S, et al. Sealants in dentistry: outcomes of the ORCA Saturday Afternoon Symposium 2007. Caries Res. 2010;44: 3–13. doi:10.1159/000271591
95. Hesse D, Bonifácio CC, Mendes FM, Braga MM, Imparato JCP, Raggio DP. Sealing versus partial caries removal in primary molars: a randomized clinical trial. BMC Oral Health. 2014;14: 58. doi:10.1186/1472-6831-14-58
96. Gomez SS, Basili CP, Emilson C-G. A 2-year clinical evaluation of sealed noncavitated approximal posterior carious lesions in adolescents. Clin Oral Investig. 2005;9: 239–243. doi:10.1007/s00784-005-0010-7
97. Morales-Chávez MC, Nualart-Grollmus Z-C. Retention of a resin-based sealant and a glass ionomer used as a fissure sealant in children with special needs. J Clin Exp Dent. 2014;6: e551–e555. doi:10.4317/jced.51688
98. Ammari MM, Soviero VM, da Silva Fidalgo TK, Lenzi M, Ferreira DMTP, Mattos CT, et al. Is non-cavitated proximal lesion sealing an effective method for caries control in primary and permanent teeth? A systematic review and meta-analysis. J Dent. 2014;42: 1217–1227. doi:10.1016/j.jdent.2014.07.015
99. Chen Y, Chen D, Lin H. Infiltration and sealing for managing non-cavitated proximal lesions: a systematic review and meta-analysis. BMC Oral Health. 2021;21: 13. doi:10.1186/s12903-020-01364-4
100. Bakhshandeh A, Ekstrand K. Infiltration and sealing versus fluoride treatment of occlusal caries lesions in primary molar teeth. 2-3 years results. Int J Paediatr Dent. 2015;25: 43–50. doi:10.1111/ipd.12096
101. Ekstrand KR, Bakhshandeh A, Martignon S. Treatment of Proximal Superficial Caries Lesions on Primary Molar Teeth with Resin Infiltration and Fluoride Varnish versus Fluoride Varnish Only: Efficacy after 1 Year. Caries Res. 2010;44: 41–46. doi:10.1159/000275573
102. El Meligy OAES, Alamoudi NM, Eldin Ibrahim ST, Felemban OM, Al-Tuwirqi AA. Effect of resin infiltration application on early proximal caries lesions in vitro. J Dent Sci. 2021;16: 296–303. doi:10.1016/j.jds.2020.04.005
103. Arslan S, Kaplan MH. The Effect of Resin Infiltration on the Progression of Proximal Caries Lesions: A Randomized Clinical Trial. Med Princ Pract. 2020;29: 238–243. doi:10.1159/000503053
104. Chatzimarkou S, Koletsi D, Kavvadia K. The effect of resin infiltration on proximal caries lesions in primary and permanent teeth. A systematic review and meta-analysis of clinical trials. J Dent. 2018;77: 8–17. doi:10.1016/j.jdent.2018.08.004
105. Arslan S, Lipski L, Dubbs K, Elmali F, Ozer F. Effects of different resin sealing therapies on nanoleakage within artificial non-cavitated enamel lesions. Dent Mater J. 2018;37: 981–987. doi:10.4012/dmj.2017-027
106. Yoshiyama M, Tay F, Doi J, Nishitani Y, Yamada T, Itou K, et al. Bonding of Self-etch and Total-etch Adhesives to Carious Dentin. J Dent Res. 2002;81: 556–60. doi:10.1177/154405910208100811
107. Schwendicke F, Frencken JE, Bjørndal L, Maltz M, Manton DJ, Ricketts D, et al. Managing Carious Lesions: Consensus Recommendations on Carious Tissue Removal. Adv Dent Res. 2016;28: 58–67. doi:10.1177/0022034516639271
108. Innes NPT, Frencken JE, Bjørndal L, Maltz M, Manton DJ, Ricketts D, et al. Managing Carious Lesions: Consensus Recommendations on Terminology. Adv Dent Res. 2016;28: 49–57. doi:10.1177/0022034516639276
109. Banerjee A, Frencken JE, Schwendicke F, Innes NPT. Contemporary operative caries management: consensus recommendations on minimally invasive caries removal. Br Dent J. 2017;223: 215–222. doi:10.1038/sj.bdj.2017.672
110. Verdugo-Paiva F, Zambrano-Achig P, Simancas-Racines D, Viteri-García A. Selective removal compared to complete removal for deep carious lesions. Medwave. 2020;20. doi:10.5867/medwave.2020.01.7758
111. Barros MMAF, De Queiroz Rodrigues MI, Muniz FWMG, Rodrigues LKA. Selective, stepwise, or nonselective removal of carious tissue: which technique offers lower risk for the treatment of dental caries in permanent teeth? A systematic review and meta-analysis. Clin Oral Investig. 2020;24: 521–532. doi:10.1007/s00784-019-03114-5
112. Schwendicke F, Paris S, Tu Y-K. Effects of using different criteria for caries removal: a systematic review and network meta-analysis. J Dent. 2015;43: 1–15. doi:10.1016/j.jdent.2014.10.004
113. Göstemeyer G, da Mata C, McKenna G, Schwendicke F. Atraumatic vs conventional restorative treatment for root caries lesions in older patients: Meta- and trial sequential analysis. Gerodontology. 2019;36: 285–293. doi:10.1111/ger.12409
114. Tonprasong W, Inokoshi M, Shimizubata M, Yamamoto M, Hatano K, Minakuchi S. Impact of direct restorative dental materials on surface root caries treatment. Evidence based and current materials development: A systematic review. Jpn Dent Sci Rev. 2022;58: 13–30. doi:10.1016/j.jdsr.2021.11.004